Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.

Although there was no decrease in parasite egg burden (as determined by recovery of ova from the liver), the viability of these eggs from trial 1 was examined and highly significant ( P < 0.0001) reductions in hatching capability (68% and 56%) were observed for the Rubb 12 -tri- and Rubb 7 -tnl-treated mice, respectively ( Fig 8C ).

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