Odor cueing during slow-wave sleep benefits memory independently of low cholinergic tone.

Estimates of EEG power reflected the group differences in sleep architecture with a significant reduction of slow-oscillation power in the physostigmine group at all three electrode sites (main effect “physostigmine/placebo”: frontal p = 0.021, η p 2 = 0.20; central: p = 0.019, η p 2 = 0.21; parietal: p = 0.025, η p 2 = 0.19) and a marginally significant reduction in delta band power (frontal: p = 0.065, η p 2 = 0.14; central: p = 0.040, η p 2 = 0.16; parietal: p = 0.058, η p 2 = 0.14, see Online Resource 2 ).

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vehicle: p = 0.013, d = 0.77) and failed to reach significance in the physostigmine group (odor vs. vehicle: p = 0.31, d = 0.27).

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