Among these mechanisms, the release of transforming growth factor (TGF)-beta and Th2 cytokine production, ameliorate myelination ( 25 ), inhibiting B and T cell migration through the blood brain barrier ( 26 ), increasing cytokine levels such as interleukin (IL)-10, tumor necrosis factor-alpha, and IL-4 ( 27 ) and decrease in matrix metalloproteinase activity ( 28 ) may be significant.
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Co-Transplantation of Human Neurotrophic Factor Secreting Cells and Adipose-Derived Stem Cells in Rat Model of Multiple Sclerosis.
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