Remarkably there is a highly significant depletion of Fusobacterium periodonticum, Leptotrichia trevisanii, Leptotrichia hofstadii , and Leptotrichia buccalis in HNSCC compared to controls in the JHU cohort ( Supplementary Figure 2A- 2E ).
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High-resolution microbiome profiling uncovers <i>Fusobacterium nucleatum</i>, <i>Lactobacillus gasseri/johnsonii</i>, and <i>Lactobacillus vaginalis</i> associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation.
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