Barely Significant
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Potential utility of a longitudinal relative dose intensity of molecularly targeted agents in phase 1 dose-finding trials.

Cancer Sci · 2018 · PMC5765308 · PMID 29114963

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0.0670
closest p · 1.3× alpha
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marginally significantP = .067so close (0.05 < p ≤ 0.1)
No associations between the dose group (or average RDI) and response rate were found in the multivariate logistic regression analysis (Table S4 ), but the difference in the response rate between the 2 groups (ie, 10.9% of RP2D group vs 1.9% of OLLD group) was shown to be marginally significant by Fisher's exact test ( P = .067).

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