Transcriptional inaccuracy threshold attenuates differences in RNA-dependent DNA synthesis fidelity between retroviral reverse transcriptases.

However, when the commercial enzyme is used, the pH and Mg 2+ concentration had a relatively small influence in the error rate (2.5 × 10 −5 , with RNAs obtained at pH 7.9/6 mM Mg 2+ ) while differences may not be significant.

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