Advance in plasma SEPT9 gene methylation assay for colorectal cancer early detection.

World J Gastrointest Oncol · 2018 · PMC5767789 · PMID 29375744

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highly significantno p-value reported

A study published by Tänzer et al[ 44 ] demonstrated the combined analysis of methylation status of SEPT9 and ALX4 to be highly significant in the detection of colorectal polyps with a sensitivity and specificity reaching 71% and 95%, respectively, indicating the potential use of the combined methods in detecting advanced precancerous colorectal lesions.

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an increasing trendno p-value reported

Combined detection of the SEPT9 assay with other colorectal cancer detection tests The combination of multiple methods or markers has become an increasing trend in CRC detection and screening.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.