Causal associations between risk factors and common diseases inferred from GWAS summary data.

Nat Commun · 2018 · PMC5768719 · PMID 29335400

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highly significantno p-value reported

The effect of LDL-c on Alzheimer’s disease (AD) was highly significant without HEIDI-outlier filtering (OR = 1.35 and P GSMR = 7.8 × 10 −16 ) (Fig. 4 ).

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