25 Ibrutinib patients with mutated IGHV showed a slight trend to greater initial increase in absolute lymphocyte count (ALC) compared with those with unmutated IGHV ( Supplementary Figure 6 ), with apparent slower resolution in patients with mutated IGHV vs those with unmutated IGHV similar to a previous report ( P <0.001). 26 The best ORR increased in the ib
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Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL.
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