∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling.

Nat Commun · 2018 · PMC5772473 · PMID 29343721

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not quite reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

For sarcomas, 3/6 Δ122/Δ122 IL-6+/+ mice showed metastases to the gut, liver, spleen, pancreas or lymph node; 1/3 of Δ122/Δ122 IL-6+/− mice had a single metastasis to the heart; and 0/4 Δ122/Δ122 IL-6−/− mice had metastases, although this did not quite reach statistical significance ( p = 0.09, χ 2 -test; Table 2 ) due to low numbers of tumours.

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