Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa.

falciparum -infected children (3–15 years) were dosed on D3 with 0.75 mg base/kg of PQ, four G6PDd hemizygous males showed an increasing trend of a higher decline (median ~ -22%) in the fractional Hb on D7 compared to the 39 G6PD normal and nine G6PDd heterozygous females, who had median Hb falls of ~ -5% [ 66 ].

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