Analysis of the tonsillar microbiome in young adults with sore throat reveals a high relative abundance of Fusobacterium necrophorum with low diversity.

Analysis of alpha diversity for GAS with high OTU values compared to other patient groups reveals only a marginally significant difference between any two groups with Phylogenetic Diversity–Whole Tree and no significant difference among the remaining four alpha diversities, no matter whether we choose OTU abundance > 0.05 or >0.1 as the threshold for subgroup "positive_high" ( Table 3 , Table K in S1 File and Table U in S1 File ).

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