In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of <i>Mycobacterium tuberculosis</i>.

Proc Natl Acad Sci U S A · 2018 · PMC5776797 · PMID 29255022

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0582

boldest claim

The sentences

highly significantP = 0.0001actually significant

Furthermore, quantification revealed a highly significant ( P = 0.0001) fourfold reduction in the average number of Kyn + cells in D-1MT–treated animals ( Fig. 3 B ).

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approached near significanceP = 0.0582so close (0.05 < p ≤ 0.1)

4 B ) in treated animals, relative to untreated animals, the IFN-γ levels approached near significance ( P = 0.0582) between the two groups in BAL.

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