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Risk Factors, Regional Disparity and Trends of Ischemic Stroke Etiologic Subtypes.

Chin Med J (Engl) · 2018 · PMC5776840 · PMID 29336358

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a decreasing trendno p-value reported
It was found that except for nonlacunar infarction, which showed a decreasing trend, the changes in other subtypes were not significant.[ 24 ] Since it did not report change of risk factor in the Japanese research, hospital-based studies were mainly compared and discussed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.