Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes.

Proc Natl Acad Sci U S A · 2018 · PMC5777065 · PMID 29279367

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highly significantno p-value reported

However, unlike spinal cord and cerebellar astrocytes, optic nerve astrocytes showed a highly significant difference in expression of genes in the complement system pathway ( Fig. 4 A and Table S3 ), revealing region-specific differences in inflammation in astrocytes during EAE.

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