Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.

J Am Heart Assoc · 2017 · PMC5778957 · PMID 29288159

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

a trend toward significanceP =0.08so close (0.05 < p ≤ 0.1)

Replication We tested the association between the rs6078905 SNP and HCTZ BP response in PEAR blacks and we found a trend toward significance with DBP response ( P =0.08) and SBP response ( P =0.17; Figure 2 ).

also in 3,729 other papers

may not be significantno p-value reported

In blacks, because of the differences in recombination rates and linkage disequilibrium patterns between blacks and whites, SNPs identified in whites may not be significant in blacks; however, other SNPs in the region may show significant association with the phenotype.

also in 2,774 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.