Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting.

For example, mice maintained on ADF for three months prior to transient occlusion of the middle cerebral artery (an animal model of focal ischemic stroke) exhibit highly significant reductions in brain damage and neurological deficits, and a reduction in stroke-induced reactive neurogenesis.( 112 ) The underlying mechanisms likely involve both activation of adaptive stress response signaling pathways in neurons by neurotrophic factors and neurotransmitters,( 112 ) and circulating factors.

also in 132,142 other papers