Hydroxychloroquine decreases human MSC-derived osteoblast differentiation and mineralization in vitro.

J Cell Mol Med · 2018 · PMC5783866 · PMID 28975700

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highly significantno p-value reported

Microarray analysis and additional PCR validation revealed a highly significant up‐regulation of the cholesterol biosynthesis, lysosomal and extracellular matrix pathways in the 5 μg/ml HCQ‐treated cells compared to controls.

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