Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer.

Sci Rep · 2018 · PMC5784122 · PMID 29367611

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highly significantP = 5.2 × 10 6a dropped decimal point

We found highly significant SNPs in ABCC2 , a known carboplatin transporter, associated with carboplatin clearance (asymptotic P = 5.2 × 10 6 , empirical P = 1.4 × 10 −5 ), indicating biological plausibility.

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