Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects.

BMC Med Genomics · 2018 · PMC5784607 · PMID 29368655

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1054

boldest claim

The sentences

a marginal trend toward significanceP = 0.05actually significant

Furthermore, SKAT showed a marginal trend toward significance after Bonferroni correction with Joubert Syndrome ciliopathy genes ( P = 0.05).

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marginal significanceP = 0.1054not close (p > 0.1)

Analysis of ciliopathy genes and their subsets The SKAT rare variant association test between the case ( n = 13) and control ( n = 30) groups showed marginal significance for JBTMKS after Bonferroni correction ( P = 0.1054, Table 3 ) from the Invitae.

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