The effect of concomitant DPPIVi use on glycaemic control and hypoglycaemia with insulin glargine 300 U/mL (Gla-300) versus insulin glargine 100 U/mL (Gla-100) in people with type 2 diabetes: A patient-level meta-analysis of EDITION 2 and 3.

As with the less stringent glucose threshold, individual reductions in risks for the stricter (<3.0 mmol/L [<54 mg/dL]) threshold achieved statistical significance in the ‘without DPPIVi’ subgroup and did not achieve significance in the ‘with DPPIV’ subgroup ( S2 Table and Fig 3 ).

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