Prostaglandin receptors induce urothelial tumourigenesis as well as bladder cancer progression and cisplatin resistance presumably via modulating PTEN expression.

Br J Cancer · 2018 · PMC5785746 · PMID 29123257

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a trend towards significanceno p-value reported

In muscle-invasive tumours, however, EP2 positivity (hazard ration (HR)=6.452, P =0.069) and EP4 positivity (HR=5.604, P =0.022) showed a trend towards significance and statistical significance, respectively, for cancer-specific mortality.

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