Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus.

Arthritis Res Ther · 2018 · PMC5785891 · PMID 29370834

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highly significantno p-value reported

In this regard, the decreased accumulation of macrophages, T cells, and B cells in the choroid plexus was highly significant and very encouraging.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.