Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.

This increase in inflammation markers was corroborated by increased total cell numbers in the BAL of ozone-treated Pgam5 − / − compared to control animals, most strikingly being a highly significant increase in neutrophils in Pgam5 − / − mice as compared to controls ( Fig. 5b , Supplementary Fig. 5b ).

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