Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires.

Front Immunol · 2018 · PMC5786517 · PMID 29403498

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highly significantno p-value reported

Interestingly, and highly significant, 20 of 23 Vh1-26/Vk4-74-expressing ANAs derived from aging B6 mice had a serine to arginine mutation at position 30 in the CDR1 region of the Vk4-74 gene.

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