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Pharmacokinetic Behavior of Phenytoin in Head Trauma and Cerebrovascular Accident Patients in an Iranian Population.

J Res Pharm Pract · 2017 · PMC5787907 · PMID 29417081

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a decreasing trendno p-value reported
Plasma concentration of phenytoin did not differ significantly in patients with severe TBI in comparison with patients with moderate TBI while there was no significant difference between the CVA and the HT groups for APACHE II scores at the baseline and the sampling days, a decreasing trend was observed for these scores.

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