A Network Meta-Analysis Comparing Effects of Various Antidepressant Classes on the Digit Symbol Substitution Test (DSST) as a Measure of Cognitive Dysfunction in Patients with Major Depressive Disorder.

Int J Neuropsychopharmacol · 2018 · PMC5793828 · PMID 29053849

Europe PMC DOI

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clearly significantlyno p-value reported

It should also be noted that vortioxetine is very clearly significantly better than placebo, due to the relatively large number of patients in trials with both vortioxetine and placebo.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.