Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy.

Sci Rep · 2018 · PMC5794986 · PMID 29391529

Europe PMC DOI

hedged sentences

0.0014

closest p · 0.0× alpha

0.0547

boldest claim

The sentences

highly significantp = 0.0014actually significant

The differences among the four groups were highly significant in the soleus for unlabeled type I (Kruskal-Wallis Chi2 (3ddl) p = 0.0014) and type IIa fibers (p = 0.0025), and in the plantaris, for type IIa fibers (p = 0.0011).

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almost significantp = 0.0547so close (0.05 < p ≤ 0.1)

In the soleus of SMA mice, the effect of flunarizine was significant with unlabeled type I fibers, which are presumably type II fibers, (1ddl, p = 0.0039) and almost significant for type IIa fibers (p = 0.0547).

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