The TLR9 agonist MGN1703 triggers a potent type I interferon response in the sigmoid colon.

Mucosal Immunol · 2018 · PMC5796873 · PMID 28766555

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a nonsignificant trendno p-value reported

We also observed a nonsignificant trend in this cohort towards a lower firmicutes to bacteroidetes ratio following MGN1703 dosing.

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