Barely Significant
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The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance.

Sci Rep · 2018 · PMC5797153 · PMID 29396404

Europe PMCDOI
1
hedged sentence
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

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highly significantp < 0.0001actually significant
However, when we transiently expressed a constitutively active form of Rab8a, using the same promoter (t aCP:mCherry-Rab8aCA ), we observed highly significant rescue of OS development in the mutant PRs expressing this transgene (Fig. 6D–D’ and red circles in E, p < 0.0001, Student’s t -test), with a majority of expressing PRs now displaying a nicely elongated OS.

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