highly significantp < 0.001
Statistically significant changes were classified as significant ( ∗ ) where p < 0.05, more significant ( ∗∗ ) where p < 0.01 and highly significant ( ∗∗∗ ) where p < 0.001.
Statistically significant changes were classified as significant ( ∗ ) where p < 0.05, more significant ( ∗∗ ) where p < 0.01 and highly significant ( ∗∗∗ ) where p < 0.001.