Retargeting of UniCAR T cells with an <i>in vivo</i> synthesized target module directed against CD19 positive tumor cells.

Oncotarget · 2018 · PMC5800918 · PMID 29484126

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highly significantno p-value reported

Soon after antigen contact, the adoptively transferred CAR T cells will expand and produce inflammatory cytokines which can cause a clinically highly significant cytokine storm.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.