DNA methylome profiling at single-base resolution through bisulfite sequencing of 5mC-immunoprecipitated DNA.

BMC Biotechnol · 2018 · PMC5801686 · PMID 29409498

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an elevated trendno p-value reported

Furthermore, we found that the methylation level of total cytosine on genome had an elevated trend in MB-seq (Fig. 6c ) because unmethylated fragments were not captured by the antibody and thus the methylation level was over-estimated compared to BS-seq.

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