Jagged1-induced Notch activation contributes to the acquisition of bortezomib resistance in myeloma cells.

Blood Cancer J · 2017 · PMC5802593 · PMID 29242532

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barely significantno p-value reported

By contrast, the effects of Gö6976, an inhibitor of PKCα and β, and enzastaurin, a specific inhibitor for PKCβ, were barely significant, and they did not affect the Jagged1-Notch-mediated enhanced survival of myeloma cells against BTZ.

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