Barely Significant
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The evolution of the epidemiological landscape of head and neck cancer in Italy: Is there evidence for an increase in the incidence of potentially HPV-related carcinomas?

PLoS One · 2018 · PMC5802923 · PMID 29415020

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highly significantno p-value reported
The rise in the numbers of women smoking that was registered in Italy until 1990 may explain the overall stable figures with only a slight, although significant, decrease noted for this site in the women over 60, as compared to the highly significant decline involving all age classes in the men.

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