Soluble HLA-G also causes monocyte differentiation to immunosuppressive M2 macrophages, which may be significant in a tumor microenvironment with active CMV infection [ 108 , 110 ].
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New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection.
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