Conformational states during vinculin unlocking differentially regulate focal adhesion properties.

Representative images and the corresponding quantification of FA features, based on quantification of approximately 1,000 FAs in each experimental group, revealed highly significant differences in FA area (Fig. 5B and Supplementary Figure 2B ), length (Fig. 5C and Supplementary Figure 2C ), dynamics (Figure S3 ) and number (Fig. 5D and Supplementary Figure 2D ) which were consistent in both the HeLa cells (Supplementary Figure 2 ) and the vinculin null MEFs (Fig. 5 ).

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