Poly-arginine R18 and R18D (D-enantiomer) peptides reduce infarct volume and improves behavioural outcomes following perinatal hypoxic-ischaemic encephalopathy in the P7 rat.

Mol Brain · 2018 · PMC5810179 · PMID 29426351

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highly significantno p-value reported

The efficacy of both R18 and R18D over a wide dose range (30–1000 nmol/kg) is highly significant, which ultimately could translate to the peptides being effective at low doses when used clinically following HIE.

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