Glial hypothalamic inhibition of GLUT2 expression alters satiety, impacting eating behavior.

Similarly, the eating rate, estimated as the total amount of food consumed in total meal duration, showed that Ad‐shGLUT2 rats had a higher eating rate (Figure 8 c), which correlated with the highly significant increase in food intake (Figure 7 b). 4 DISCUSSION Here, we show that GLUT2 inhibition in tanycytes disrupted the hypothalamic glucosensing mechanism that controls feeding behavior.

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