Nocturnal Hypoxia Improves Glucose Disposal, Decreases Mitochondrial Efficiency, and Increases Reactive Oxygen Species in the Muscle and Liver of C57BL/6J Mice Independent of Weight Change.

Of note, ROS production in the liver of obese mice was almost three times higher than that in lean mice, despite only a nonsignificant trend for reduction in liver RCR, suggesting that liver ROS production may be more dependent on nonmitochondrial sources in obese mice compared to lean mice.

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