Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson's disease: a genetic association study.

BMC Neurol · 2018 · PMC5822630 · PMID 29466944

Europe PMC DOI

hedged sentence

0.0360

closest p · 0.7× alpha

0.0360

boldest claim

The sentences

marginal significancep = 0.036actually significant

Repeating the same analysis in the independent PPMI dataset for rs3756063, we replicated the same result with marginal significance (one-sided p = 0.036, odds ratio 1.35), yet strikingly similar effect size and allele frequencies across groups.

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