Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis.

PLoS One · 2018 · PMC5823380 · PMID 29470488

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

a substantial trend toward significancep = 0.051so close (0.05 < p ≤ 0.1)

When hippocampal and cortical cultures were pre-treated with dorsomorphin, an inhibitor of BMP-2 signaling, Smad 1/5/8 phosphorylation diminished with a substantial trend toward significance (p = 0.051).

also in 2 other papers

approached acceptable levels of statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

Although an increase in BMP-2 responsiveness that approached acceptable levels of statistical significance (p = 0.052) was observed ( Table 6 ), further investigation may be necessary before making an explicit conclusion regarding the morphogen sensitivity of hippocampal cells in the context of iAβ expression.

also in 0 other papers

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