Barely Significant
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Damaging de novo mutations diminish motor skills in children on the autism spectrum.

Proc Natl Acad Sci U S A · 2018 · PMC5828599 · PMID 29434036

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highly significantno p-value reported
However, even when we weight mutation and target as above, we do not see a highly significant correlation between nvIQ and missense mutation.

also in 132,142 other papers

marginal significanceno p-value reported
The association of impaired motor skills with missense mutation has marginal significance at best.

also in 5,069 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.