This overlap was highly significant as measured by Jaccard similarity index, which was 12.9% for SIs and 19.2% for MIs between Sox17-1 and BAC5, in comparison to 0–5.2% between sox17-3 and BAC5 and 1.9% to 7.4% between sox17-3 and sox17-1.
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Bacterial artificial chromosomes establish replication timing and sub-nuclear compartment de novo as extra-chromosomal vectors.
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