TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium.

Sci Rep · 2018 · PMC5830574 · PMID 29491434

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a decreasing trendno p-value reported

Although increases in Cox2 displayed a decreasing trend following TRPV4 inhibition, a significant increase in Cox2 was still achieved in response to OFS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.