Barely Significant
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Crystal structure correlations with the intrinsic thermodynamics of human carbonic anhydrase inhibitor binding.

PeerJ · 2018 · PMC5831161 · PMID 29503769

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may be significantno p-value reported
This opportunity may be significant for the design of the isoform-specific compounds that could distinguish between very similar active sites.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.