Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer's disease.

Acta Neuropathol Commun · 2018 · PMC5831854 · PMID 29490708

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4 ), is characterized by highly significant enrichment of GO terms and proteins linked to myelin sheath (CNP, MAG, MBP, OMG, PLP1, MOG, PMP2, CLDN11, and ERMN) and the organization of paranodal and juxtaparanodal regions of axon at the node of Ranvier (MAG, ERMN, CNTNAP1, CNTN2, and KCNA2) with CNP, MAG, OMG, and PLP1 as top hub proteins (Fig. 7 and Additional file 6 : Table S6).

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