highly significantP = 0.007
A more detailed analysis was carried out using a repeated measures ANCOVA (see Methods) which revealed that the effect of the Between-Subjects DRB1*13:02 was highly significant (P = 0.007, F-test in repeated measures ANCOVA), as was the Region x DRB1*13:02 interaction (P = 0.007, Greenhouse-Geisser test), reflecting the differential effect of DRB1*13:02 on individual regions.