There are a total of five randomized, double-blind, control trials that have demonstrated efficacy of risperidone for the treatment of tics [ 42 – 46 ], yet the long-term side effects (of which hyperprolactinemia due to tubero-infundibular D2 antagonism is the most impactful) may be significant [ 9 , 47 ].
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Current Approaches and New Developments in the Pharmacological Management of Tourette Syndrome.
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