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Treatment with irbesatan may improve slit diaphragm alterations in rats with adriamycin-induced nephropathy.

J Renin Angiotensin Aldosterone Syst · 2016 · PMC5843943 · PMID 27169889

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a decreasing trendno p-value reported
At four weeks after drug intervention, the level of urinary protein excretion of the rats in the MP group was lower than that of the model group ( p =0.034), and the irbesartan group showed a decreasing trend, although there was no statistically significant difference.

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